Evaluation of the bioactive constituents and antimicrobial potentials of the ethyl acetate extract of Costus afer stem
Nna PJ, Don-Lawson DC, Agber CT
Costus afer is a perennial plant, commonly called bush sugar cane or monkey sugar cane. It can be found in the forest belts of Senegal, Guinea, Sierra-Leone, Niger, and Nigeria. In Nigeria, it is commonly found in the Western and Eastern parts. The stem of the plant was phytochemical screening for some metabolites and the quantitation of metabolites was carried out using GC-FID machine. The antimicrobial potential of the Ethyl acetate stem extract of the plant was carried out using agar diffusion method. The phytochemicals present in the stem back of the plant include, alkaloids, saponins, flavonoids, tannins, cardiac glycosides and triterpenoids. Quantitation of these phytochemicals showed that flavonoids represent the highest quantity of all. Most of the test organisms were susceptible to the extract with zones of inhibition that ranged between 6 and 26 mm, with Bacillus cereus being the most sensitive. Aspergillus niger however, showed resistivity to the extracts with an unclear zone of inhibition of 6 mm. C. afer contains a good number of important secondary metabolites that could be isolated as drugs, drugs precursors or lead compounds in drug development process. Thus, adding value to the use of this plant in traditional medicine.