Vol. 4, Issue 3 (2020)
Synthetic studies of quinoxaline derivatives
Author(s): Rajeev Kumar Karna
Abstract: In this paper, 2-ethyl-4(3H)-3, 1-benzoxazinone (1) was synthesized from acetylation with simultaneous cyclization of anthranilic acid and acetyl chloride. Compound 1 was treated with hydrazine hydrate to yield 3-amino-2-ethyl-4(3H)-quinazolinone (2). Reaction of compound 2 with aromatic aldehydes/ketones resulted Schiff bases 3-6. All newly synthesized compounds were characterized using different methods of spectroscopy such as IR, 1H-NMR and 13C-NMR.