Brinjal is often found affected by damping off disease in nursery stage. Sowing to the great loss the seedling an investigation was undertaken to manage the damping off disease of brinjal. The experiment was conducted under in vitro and pot culture conditions to observe the effects of botanicals against Pythium ultimum. Sevan treatments were taken up with three replications and data collected was analyzed using CRD. Minimum mycelial growth (mm) was observed in Neem leaf extract @ 10% (6.96mm) as compared to the untreated controls (29.36 mm). Followed by T₂ – Garlic clove extract (9.56 mm), T₄ – Dhatura leaf extract (10.76 mm), T₅ – Onion bulb extract @ 10% (11.21 mm), T₃- Turmeric extract (12.11 mm), T₆ – Ginger extract (12.87 mm) and T₇- Tulsi leaf extract (13.67 mm). In pot condition sevan treatments were taken up with two replications and data collected was analyzed using RBD. The treatments taken up were in Neem leaf extract, Garlic clove extract, Dhatura leaf extract, Onion bulb extract, Turmeric extract, Ginger extract and Tulsi leaf extract. Seeds were sown in pathogen inoculated soil @ 50 seeds per pot and irrigated daily. Pathogen alone inoculated pots served as control. The observation was recorded on 7th and 14^th days after sowing. The results revealed that soil treatment with the botanicals against damping off (Pythium ultimum) as compared to check were significant. Maximum germination per cent was recorded in Neem leaf extract @ 10% (69%) as compared to the untreated controls (27%).Followed by Garlic clove extract (63%), Dhatura leaf extract (57%), Onion bulb extract (53%), Turmeric extract (50%), Ginger extract (47%) and Tulsi leaf extract (43%), Neem leaf extract was superior as compared to other treatments.