Abiotic stress includes temperature, salinity, water, radiation, chemical, etc. Among which cold, salinity and drought are the major stresses, which adversely affects plants growth and productivity. Cellular response against stress includes reactive oxygen species (ROS), osmolytes and protein accumulation. Among protein accumulation, dehydrin belongs to group II of late embryogenesis abundance (LEA) protein. Dehydrins are considered all the proteins which have at least one copy of the lysine rich amino acids sequence known as K segment. K segment of dehydrins imparts structural modification when translocated to the plasma membrane and it forms α–helix which is amphipathic in nature. Genes which encode these proteins are expressed during late embryogenesis, as well as in vegetative tissues subjected to drought, low temperature and high salt conditions and enhance resistance of the transgenic lines to various adverse environments, such as cold, drought, salinity and osmotic stress.