Medicinal plants are therapeutically effective and culturally acceptable, since the increase in the use of synthetic chemicals in cancer therapy has led to many side effects and undesirable hazards, which led to go back to natural resources and economically within the research of the poor people. Phytochemical analysis of Rhizophora mucronata has revealed that numerous compounds traditionally used for medicinal purposes have many therapeutical properties. The phytochemical screening of the leaf extract revealed that the presence of alkaloids, tannins, steroids, terpenoids and coumarins. FT-IR spectroscopic analysis of the Ethyl acetate, Butanol and Methanol extract of Rhizophora mucronata revealed the presence of -CH, -OH, CH-OH and –NH₂ bond stretching. The results suggest that the phytochemical properties demostrated by the plant extract and leads to the isolation of new and novel compounds.