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VOL. 9, ISSUE 2 (2025)
Nanotechnology is transforming the pharmaceutical landscape by enabling targeted drug delivery, improved bioavailability, and reduced side effects
Authors
Shilpa VP, Sirrajudheen MK, Akshaya P, Fathima Rabwa PT, Jaseeda Thelakkadan
Abstract
Nanotechnology has revolutionized the
pharmaceutical landscape by enabling the development of advanced drug delivery
systems that address many limitations of conventional therapeutics.
Nanocarriers such as liposomes, polymeric nanoparticles, dendrimers, micelles,
and solid lipid nanoparticles offer unique advantages, including enhanced
solubility and permeability, controlled and sustained drug release, and the
ability to target specific tissues or cells. These features significantly
improve the bioavailability and therapeutic efficacy of drugs, particularly
those with poor solubility or challenging pharmacokinetic profiles.
Furthermore, nanocarriers can overcome biological barriers such as the
blood-brain barrier and gastrointestinal tract, expanding the range of
treatable conditions. Recent innovations in smart, stimuli-responsive, and
multifunctional nanocarriers, as well as combination therapies, are paving the
way for personalized and precision medicine. However, the development and
clinical translation of nanomedicines require rigorous safety assessments and
regulatory oversight to ensure their efficacy and minimize potential risks.
This review provides a comprehensive overview of the types, mechanisms,
advantages, challenges, and emerging trends in nanotechnology-based drug
delivery, highlighting its transformative impact on modern pharmaceutical
science.
Pages:16-21
How to cite this article:
Shilpa VP, Sirrajudheen MK, Akshaya P, Fathima Rabwa PT, Jaseeda Thelakkadan "Nanotechnology is transforming the pharmaceutical landscape by enabling targeted drug delivery, improved bioavailability, and reduced side effects". International Journal of Chemical Science, Vol 9, Issue 2, 2025, Pages 16-21
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