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VOL. 9, ISSUE 2 (2025)
Green and versatile Zn–Ce nanoparticle catalyst for Benzodiazepine phamacophore synthesis
Authors
Manojkumar Chopade
Abstract
Transition metal Zn–Ce nanoparticles were facilely synthesized and
employed as an efficient catalyst for the cyclocondensation of
phenylenediamines with ethyl methyl ketone to afford the corresponding
1,5-benzodiazepine derivative (3a) in 90% yield. This novel methodology was
further extended to the synthesis of various substituted benzodiazepine
phamacophore molecules. The desired products were obtained in good to excellent
yields (75–94%) under simple, clean and environmentally benign reaction
conditions.
Pages:61-63
How to cite this article:
Manojkumar Chopade "Green and versatile Zn–Ce nanoparticle catalyst for Benzodiazepine phamacophore synthesis". International Journal of Chemical Science, Vol 9, Issue 2, 2025, Pages 61-63
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